Blood Cancers

MDRC has complete range of modalities for diagnosis of blood cancer using blood, bone marrow and lymph node samples. Our Haemato-oncology department offers state of art facilities for diagnosing all kinds of Haemato-Lymphoid and Lymphatic disorders . Our reference lab has IVD approved Flow cytometer ( 10 colors and three laser flow cytometer ) for characterization and detection of Minimal Residual Disease (MRD) in Leukemias/Lymphomas.

OurKeyServices

Bone Marrow Aspirate, Imprints and tissue biopsies with special stains
Flow Cytometry
- Acute Leukemia Basic lineage Panel
- AML characterization panel
- ALL Characterization panel
- Acute Leukemia Comprehensive Diagnostic Panels
- CLL screening Panel
- CLL Diagnostic Panel
- MRD panels
- Multiple Myeloma Panel
- MDS panel etc
Bone Marrow Karyotyping
FISH tests
- CML (BCR-ABL)
- CLL (Chr 13q, Trisomy 12, 17p.53, 11q (ATM))
- AML (AML1-ETO, Trisomy 8, MLL, Inv(16), BCR ABL)
- MM (Chr 13q, 17p53, 11q(ATM), IgH, FGFR3/IgH)
- MDS (Del5q, Del 7q) etc
Molecular tests
- JAK2 Gene (V617F) Mutation
- FLT3 (ITD, D835Y) Mutation
- BCR-ABL1 Major Quantitative
- BCR-ABL1 Major, BCR-ABL1 Minor Qualitative
- BCR-ABL1 Minor Quantitative BCR/ABL Variant Panel (Mbcr-b2a2, b3a2, b2a3, b3a3; mbcr-e1a2, e1a3; µbcr)
- PML/RARA Qualitative and Quantitative
- RUNX1-RUNX1T1 (AML1-ETO) t(8;21)
- CBFB-MYH11 inv(16)
- TEL/AML1 MLL t(4;11)(q21;q23)
- E2A t(1;19)(q23;p13)
- ALL PCR Panel (BCR/ABL t(9;22)(q34;q11), TEL/AML1 t(12;21)(p13;q22), MLL t(4;11)(q21;q23), E2A t(1;19)(q21;q23))
- Acute Leukemia Mini Panel (AML/ETO, inv(16), PML/RARA, BCR/ABL t(9;22)(q34;q11), TEL/AML1 t(12;21)(p13;q22), MLL t(4;11)(q21;q23), E2A t(1;19)(q21;q23)
- AML PCR Panel (AML/ETO, inv(16), PML/RARA)
- BCR/ABL1 Kinase Domain Mutation Myeloproliferative Leukemia Mutation Screening
- MPL Mutation (MPL - S505N; W515L)
- JAK 2 Mutation Detection Panel (Exons 12-15)
- CEBPA Full gene sequencing
- NPM1 Mutation Analysis (Exon 12 insertion)
- CALR Mutation Analysis (Deletion or Insertion in Exon 9)
- Chronic Neutrophilic Leukemia (CNL)(CSF3R Exon 14 & 17; SETBP gene)
- GATA2 full length gene sequencing
- c-KIT Mutation Screening (Exons 9, 11, 13, 17) etc.
Oncomine Panels
USG/CT guided FNAC’s to stage many lymphomas and myelomas